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Download Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology) fb2, epub

by Andrea Manni,Michael Verderame

Download Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology) fb2, epub

ISBN: 0896039129
Author: Andrea Manni,Michael Verderame
Language: English
Publisher: Humana Press; 2002 edition (January 18, 2002)
Pages: 374
Category: Medicine & Health Sciences
Subcategory: Other
Rating: 4.6
Votes: 898
Size Fb2: 1561 kb
Size ePub: 1157 kb
Size Djvu: 1376 kb
Other formats: doc lrf lit docx


Trends in Endocrinology and Metabolism.

Trends in Endocrinology and Metabolism. Hormone replacement therapy with selective estrogen receptor modulators (SERMs) promises the highly desirable benefits of estrogen and progesterone replacement therapy, while avoiding their associated risks of breast and uterine cancer, gallbladder disease, and weight gain.

Selective estrogen receptor modulators (SERMs) are a group of structurally diverse compounds that bind to estrogen receptors and act as either estrogen agonists or antagonists, depending on the target cell and hormonal.

Contemporary Endocrinology.

Andrea Manni, Michael Verderame.

Автор: Manni Andrea, Verderame Michael Название: Selective Estrogen Receptor Modulators ISBN . This comprehensive book contains information on both basic science and clinical aspects of IGFs and their regulatory proteins, with emphasis on their relevance to cancer.

This comprehensive book contains information on both basic science and clinical aspects of IGFs and their regulatory proteins, with emphasis on their relevance to cancer. Автор: Jordan V Craig Название: Estrogen Action, Selective Estrogen Receptor Modulators and ISBN: 1848169574 ISBN-13(EAN): 9781848169579 Издательство: World Scientific Publishing Рейтинг

Selective Estrogen Receptor Modulators Estrogen Replacement Therapy methods Postmenopause drug effects Receptors . On this site it is impossible to download the book, read the book online or get the contents of a book.

Selective Estrogen Receptor Modulators Estrogen Replacement Therapy methods Postmenopause drug effects Receptors, Estrogen physiology.

Selective Estrogen Receptor Modulators (Contemporary Endocrinology). Andrea Manni, Michael Verderame.

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.

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