ISBN-13: 978-1119976097. Despite some of the issues with the structure, Toxicology and Epigenetics is an important, timely book that provides world-class, expert opinion on a broad range of topics in a fast moving highly relevant branch of toxicology. British Toxicology Society, 1 July 2013).
Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology .
Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments.
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Электронная книга: Saura Sahu C. Toxicology and Epigenetics. Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence.
p. cm. Includes bibliographical references and index. I. Sahu, Saura C. 2012010175. Print ISBN: 978-1-119-97609-7. ISBN 978-1-119-97609-7 (cloth) 1. Genetic toxicology. List of Contributors xxv. 1 Introduction 1 Saura C. Sahu. References 2. 2 Environment, Epigenetics, and Diseases 5 Robert . Cheng and Wan-yee Tang.
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Global Regulatory Perspectives. Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany. Frederic Schorsch, DVM, Msc Tox Path, DESV Ana-Path, DECVP. Bayer CropScience, Antipolis, France.
Epigenetics is the study of both heritable and non-heritablechanges in the regulation of gene activity and expression thatoccur without an alteration in the DNA sequence. Thisdynamic and rapidly developing discipline is making its impactacross the biomedical sciences, in particular in toxicology whereepigenetic differences can mean that different individuals responddifferently to the same drug or chemical.
Toxicology and Epigenetics reflects the multidimensionalcharacter of this emerging area of toxicology, describingcutting-edge molecular technologies to unravel epigenetic changes,the use of in vivo and in vitro models, as well asthe potential use of toxicological epigenetics in regulatoryenvironments. An international team of experts consider theinterplay between epigenetics and toxicology in a number of areas,including environmental, nutritional, pharmacological, andcomputational toxicology, nanomaterials, proteomics andmetabolomics, and cancer research.
Topics covered include:environment, epigenetics and diseasesDNA methylation and toxicogenomicschromatin at the intersection of disease and therapyepigenomic actions of environmental arsenicalsenvironment, epigenetics and cardiovascular healthtoxicology, epigenetics and autoimmunityocular epigenomics: potential sites of environmental impact indevelopment and diseasenuclear RNA silencing and related phenomena in animalsepigenomics – impact for drug safety sciencesmethods of global epigenomic profilingtranscriptomics: applications in epigenetic toxicology
Toxicology and Epigenetics is an essential insight intothe current trends and future directions of research in thisrapidly expanding field for investigators, toxicologists, riskassessors and regulators in academia, industry and government.