silviacolasanti.it
» » Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry

Download Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry fb2, epub

by Han van de Waterbeemd,Bernard Testa,Gerd Folkers

Download Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry fb2, epub

ISBN: 3906390160
Author: Han van de Waterbeemd,Bernard Testa,Gerd Folkers
Language: English
Publisher: Wiley-VCH; 1 edition (June 1997)
Pages: 566
Category: Medicine
Subcategory: Medicine
Rating: 4.5
Votes: 896
Size Fb2: 1702 kb
Size ePub: 1865 kb
Size Djvu: 1578 kb
Other formats: doc azw lit docx


Initially that interest lay largely within medicinal chemistry and drug design, but in the 1970s and 1980s, with increasing ecotoxicological concerns, QSAR modelling of environmental toxicities began to grow, especially once regulatory authorities became involved.

Start by marking Computer-Assisted Lead Finding and Optimization . Computer- Assisted Lead Finding and Optimization. Current Tools for Medicinal Chemistry.

Start by marking Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry as Want to Read: Want to Read savin. ant to Read. This book describes the current strategies used in computer-assisted drug design. It discusses such important topics as progress in chemometrics, molecular modeling Computer-assisted techniques are well-integrated in modern drug discovery and are used for finding new leads and optimizing receptor or enzyme affinity as well as pharmacokinetic and physicochemical properties.

Han Waterbeemd, Bernard Testa, Gerd Folkers. Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches.

oceedings{erAssistedLF, title {Computer-Assisted Lead Finding and Optimization}, author {Han van de Waterbeemd and Bernard Testa and Gerd Folkers}, year {1997} }. Han van de Waterbeemd, Bernard Testa, Gerd Folkers

oceedings{erAssistedLF, title {Computer-Assisted Lead Finding and Optimization}, author {Han van de Waterbeemd and Bernard Testa and Gerd Folkers}, year {1997} }. Han van de Waterbeemd, Bernard Testa, Gerd Folkers.

Han van de Waterbeemd, Bernard Testa, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers. Advanced Computer-Assisted Techniques in Drug Discovery (Methods and Principles in Medicinal Chemistry, Vol 3). Han Van De Waterbeemd. Download (PDF). Читать.

Computer-Assisted Lead Finding and Optimization : Current Tools for Medicinal Chemistry. by Han van de Waterbeemd, Gerd Folkers, Bernard Testa.

In: H van de Waterbeemd, Testa B, Folkers G (eds): Computer-assisted lead find and optimization: current tools for medicinal chemistry. Wiley-VCH, Basel, 29–48CrossRefGoogle Scholar. 17. Guilian W, Naibin B (1998) Structure-activity relationships for rat and mouse LD50 of miscellaneous alcohols. Chemosphere 36: 1475–1483CrossRefGoogle Scholar.

ISBN-13: 978-3906390222. The 13-digit and 10-digit formats both work.

Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties. In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches. Relatively new mathematical methods such as genetic algorithms or artificial neural networks and fuzzy logic have found their application in rational molecular design. As is amply illustrated, based on recent developments in these disciplines, important progress has been made in lead finding strategies. This is of great importance to the pharmaceutical industry. Thus, all scientists investigating quantitative structure-activity relationships in their broadest sense, in medicinal, agricultural, or environmental chemistry will benefit from this book.

Related to Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry

Download Principles of Molecular Mechanics fb2, epub

Principles of Molecular Mechanics fb2 epub

Author: Katsunosuke Machida
Category: Medicine
ISBN: 0471357278
Download Pharmaceutical Profiling in Drug Discovery for Lead Selection (Biotechnology: Pharmaceutical Aspects) fb2, epub

Pharmaceutical Profiling in Drug Discovery for Lead Selection (Biotechnology: Pharmaceutical Aspects) fb2 epub

Author: Ronald Borchardt,Edward Kerns,Christopher Lipinski,Dhrien Thakker,Binghe Wang
Category: Engineering
ISBN: 0971176795
Download Computer Assisted Studies of Chemical Structure and Biological Function fb2, epub

Computer Assisted Studies of Chemical Structure and Biological Function fb2 epub

Author: etc.,William E. Brugger,Peter Christian Jurs,Andrew J. Stuper
Category: Biological Sciences
ISBN: 0471038962
Download The Estrogen Receptor as a Target for Rational Drug Design (Molecular Biology Intelligence Unit) fb2, epub

The Estrogen Receptor as a Target for Rational Drug Design (Molecular Biology Intelligence Unit) fb2 epub

Author: Erwin v. Angerer
Category: Medicine & Health Sciences
ISBN: 3540601481
Download Computer-Assisted Management and Control of Manufacturing Systems (Advanced Manufacturing) fb2, epub

Computer-Assisted Management and Control of Manufacturing Systems (Advanced Manufacturing) fb2 epub

Author: Spyros G. Tzafestas
Category: Hardware & DIY
ISBN: 3540761101
Download Architecture Design and Validation Methods fb2, epub

Architecture Design and Validation Methods fb2 epub

Author: Egon Börger
Category: Hardware & DIY
ISBN: 354064976X